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Product |
Indications |
Market Size |
| HspE7 |
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Nearly 6,000 new cases of RRP ( over 2,300 pediatric cases and over 3,600 adult cases) were diagnosed in a 12 month period according to the most recent reported survey of U.S. otolaryngologists and bronchoesophagologists. The survey estimated that there were over 5,970 cases of active pediatric RRP for which surgery was required in the previous three years, and over 9,000 cases of active adult RRP in the U.S. |
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The incidence of genital warts is estimated at one million new cases in the U.S. each year. |
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Cervical Dysplasia and Failures of LEEP |
An estimated 1.2 million women each year are diagnosed with low-grade cervical dysplasia in the U.S. Another estimated 200,000 to 300,000 women are diagnosed with high-grade cervical dysplasia in the U.S. each year, with approximately 30,000 patients failing to adequately respond to the LEEP proceedure |
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HPV Infection in Immunocompromised Patients |
Recurrence of HPV-associated diseases after treatment is especially common in HIV-infected HPV patients. For example, 39% to 62% of HIV-positive women have recurrences of CIN, compared with 9% to 18% of HIV-negative women. |
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Cervical Cancer |
In 2003, the American Cancer Society estimated that approximately 12,200 women in the U.S. would be diagnosed with invasive cervical cancer and that about 4,100 patients would die from the disease. Globally, an estimated 400,000 new cases of cervical cancer are identified each year. |
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Head and Neck Cancer |
Worldwide, there are an estimated 600,000 head and neck cancer cases reported in men and 270,000 cases reported in women annually. |
| New CoVal fusion |
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Between 150,000 and 450,000 new cases in the U.S. per year (Scrips) |
| New CoVal fusion |
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Every year, 10 percent to 20 percent of Americans get sick with the flu (influenza). In the United States, approximately 25 percent of the population has flu-associated illness annually, leading to an average of 20,000 to 40,000 deaths per year. The U.S. Centers for Disease Control and Prevention (CDC) estimates that 35 to 50 million Americans come down with the flu during each flu season, which typically lasts from November to March. |
Sources: 1 million GW (NIAID); 200,000-300,000 CIN
II/III (CDC); 5,500 RRP (Am. Soc. Ped. Otol.); approx. 500,000
AIN
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